【摘要】 本研究证实,S₁₃₀肉瘤（腹水型）、肝癌及CCl₄慢性中毒致免疫功能损伤的BALB/C小鼠均伴有血清T₃,T₄明显降低。用小剂量甲状腺片1.2（μg·g）/d治疗后,见血清T₃,T₄逐渐恢复,并伴有巨噬细胞-胸腺淋巴细胞受体活性变化、吞噬活性升高,脾NK细胞自然杀伤效应增强及溶血素抗体测定OD值增高等免疫指标的改变。表明小剂量甲状腺素对免疫损伤鼠及荷瘤鼠有免疫调节的生物活性作用。更多还原

【Abstract】 This study has confirmed a phenomena that the impairment of immune function caused by S₁₈₀sarcoma,liver cancec and CCl₄ is rela-ted with the reduction of serum T₃,T₄.After treatment with small dosageof thyroid Tab.（1.2μg·g/d）,it was found that T₃,T₄ shown a normal level accompained a markedly raise of Mφ-ThyL receptor activity and phag-ocytic activity of Mφ.Also the natural killing effect of spleen NK cell of mice was enhanced as well as the raise of OD value of hemolytic anti-body and other immune index.It was demonstrated that thyroxine has an affirm effect of immunoregulation for tumor-bearing mice and immuno-injured mice.更多还原