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RBC膜铁蛋白的免疫检测及在CRF中的初步研究

Immunoassay of RBC Membrane Ferritin and Preliminary Research in Patient with CRF

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【作者】 陈泮藻董伟李振甲徐树槐秦学清

【Author】 Chen Panzao et al(Institute of Basic Medical Science Research, The China Great Wall Hospital, Beijing)

【机构】 中国长城医院基础所航天部中心医院心肾科航天部中心医院心肾科 北京 100853北京 100853北京 100853

【摘要】 本文应用免疫印迹法,观察到CRF患者红细胞膜上有铁蛋白。铁蛋白的RIA测定结果表明:CRF组红细胞膜上铁蛋白含量明显高于对照组(P<0.001),而且与Hb呈负相关(r=-0.637);与血清Cr和BUN呈正相关(r=0.535和r=0.712)。提示患者RBC膜铁蛋白含量的改变,具有一定的临床意义。

【Abstract】 In the paper, membrane ferritin (MF) was analysed by using of immu-noblot method. The result was indicated that there was the ferritin of RBC membrane in patient with CRF, Membrane ferritin concentrations were also measured by sensitive RIA. It is shown that RBC-MF levels in CRF group were higher more than that in control group (P<0.001) . There was a negative correlationship between MF level and Hb (r =-0.637) t There also was a positive correlationship between MF level and Or, BUN (r =0.535 and r =0.712) .Above results show that there is a clinical significance in chang of RBC-MF levels.

【关键词】 红细胞膜铁蛋白慢性肾功能衰竭
【Key words】 RBC membraneFerritinChronic renal failure
  • 【文献出处】 免疫学杂志 ,Immunological Journal , 编辑部邮箱 ,1991年04期
  • 【下载频次】19
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