【摘要】 本文报告了应用免疫扩散和放射免疫方法测定先天愚型Cu—Zn SDD含量(以正常儿童和非先天愚智能发育不全患儿为对照组)的结果。结果表明行先天愚型Cu—zn SDD含量呈现基因剂量效应。该方法可用于先天愚型的临床诊断和作为先天愚与非先天愚智能发育不全的鉴别诊断。更多还原

【Abstract】 Erythrocyte superoxide dismutase contents were. measured in Down’s Syndrome patients, mentally retarded children other than Down’s Syndrome, and normal. children with immunodiffusion and radioimmunoassay. The result revealed that there is a gene dosage effect in trisomy 21. These assay methods may be employed for clinic diagnosis and differential diagnosis of Down’s Syndrome.更多还原