【摘要】 本文对204例口腔鳞癌病员进行年龄分组,做DNGB皮试及T淋巴细胞亚群测定,并进一步随访观察预后。结果发现年龄90岁以上组的老年病员DNGB反应阳性率（38.7％）明显低于30～59岁组中的青年病员（63.6％）（P<0.01）。T细胞亚群测定老年组14例,中青年组10例,老年组辅助性T细胞（CD₄）明显低于中青年组（P<0.05）。随访196例病员,发现DNGB反应与预后有关,健在者的DNGB反应阳性率（58.4％）明显高于带瘤或死亡者（40.5％）（P<0.05）。但是,未发现年龄与预后有关。更多还原

【Abstract】 We studied 204 patients with squamous cell carcinoma of the oral cavity and separated the subjects by age into 2 categories: the elderly group (age above 60) and.the younger group (age between 30 and 59) We performed DNCE test and found that the DNCB reaction of the elderly group (38.7%) was significantly lower than that of the younger group (63.6%) (p<0.01), We then performed T lymphocyte subpopulation analysis on 14 cases of the elderly group and 10 cases on the younger group, and found that the relative ration of the T helper (CD) cells of the elderly group was also lower than that of the younger group (p<0.05).In the folllow-up of 196 patients, we found that the DNCB reaction correlates with the prognosis of-these patients.The disease-free survivors had an overall better DNCB response rate (58.4%) than those with recurrent cancer or those who died (40.5%) (p<0.05).However, we had not established a relationship between age and the prognosis of squamous cell carcinoma of the oral cavity.更多还原