【摘要】 小鼠噪声暴露（3.5KH_z,103dB）60min时,肝糖原含量.饱食鼠噪声组显著低于对照组（P<0.01）,事先腹腔注入Vit B₁₂、C各组高于噪声组（P<0.05）,接近对照组（P>0.05）;饥饿鼠噪声组.Vit B₁₂和C组均高于对照组（P<0.05和P<0.01）。肝GPT活性:饱食鼠噪卢组显著高于对照组（P<0.01）,而Vit B₁₂ C和E各组与对照组无差异。饥饿鼠各组间比均无差导。说明Vit B₁₂C和E均有对抗噪声引起饱食鼠肝糖原含量下降和阻碍噪声所致饱食鼠肝GPT活性上升等作用。更多还原

【Abstract】 In this experiment, the changes of mice liver glycogen content ( MLGC ) and mice liver GPT activity ( MLGA ) were observed, which replenished with vitamins B12, C and E in satiated and starved states caused by noise exposure. Noise parameters; Noise level, 103 dB; Frequency spen, 3.5KHz; Duration, 60 min.Satiated mice were randomly divided into 7 groups. Group 1 was applied to blank control. Group 2 was usde as noise control. Groups 3,4,5,6 and 7 were added with vitamins B12 300μg, B12 200μg, C 303 mg, C 200 mg and E 100 mg/kg BW and exposed to noise. Starved mice were separated into 4 groups. Groups 1’, 2’, 3’, and 5’, were idem.The results showed that 1. MLGC of satiated mice in groups 3, 4, 5 and 6 increased in comparison with that of group 2 (P<0.05), but was close to that of group 1 (P>0.05) . MLGC of starved mice in groups 2’, 3’and 5’ was higher than that of group 1’ (P<0.05 and P<0.01 ) . 2. MLGA of satiated mice in groups 3, 4, 5,6 and? was close to that of group 1(P>0.05) . MLGA of starved mice in each group has no significant changes compared with that of group 1 (P>0.05) . It is suggested that vitamins B12, C and E all eleyate MLGC of satiated and starved mice, and decrease MLGA of satiated mice, but have no change of MLGA in starved mice.更多还原