【摘要】 用牛肾小血管匀浆粗提物免疫家免致Ⅱ型变态反应引起血管损伤。早期弹力膜已发生变性,再生后又再损伤直至140天开始有较正常膜出现。膜内侧及基底膜两侧未见沉积物,膜的损伤是抗体在原位与抗原结合产生的,膜改变严重处内皮及平滑肌细胞病变明显,膜增厚及内膜中弹力纤维增生为一种恢复期表现。再生中可呈不正常修复现象。更多还原

【Abstract】 TvpeⅡ allergic reaction, which induced vascular damage, was produced by immunizing rabbits with coarse homogenate extract of small vessels of bovine kidneys. Degeneration of the elastic membranes appeared in the early stage and was followed by regeneration and redamage, relatively normal membranes were seen until the 140th day. No deposits were found along the inner side of the elastic membrane and both sides of basement membranes, the injury of the membranes was induced by combination of antigen and antibody in situ. The changes of the endothelial cells and smooth muscle fibers were obvious in the area where membrane damage was severe. The thickening of the membranes and the regeneration of the intimal elastic fibers were the manifestation of the restoration stage. Unnormal repair could happen in the process of regeneration.更多还原