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儿童深部真菌病机体防御反应及免疫器官的改变(附64例分析)

Defense Reactions of Host and Changes of Immune Organs in Children with Deep Mycosis:An Analysis of 64 Cases

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【作者】 章敏周莉于东海王延复

【Author】 Zhang Min et al (Department of Pathology)

【机构】 哈尔滨医科大学病理学教研室哈尔滨红十字儿童医院病理科哈尔滨红十字儿童医院病理科

【摘要】 本文分析了64例儿童深部真菌病的免疫器官,将胸腺、脾、淋巴结、阑尾、扁桃体的萎缩程度划分为Ⅰ、Ⅱ、Ⅲ级。胸腺表现小体集中、囊性变、钙化,解体严重者成串小体解体消失。其他器官中相当非胸腺依赖区的萎缩则不如胸腺依赖区明显。分析了真菌侵入的局部反应与全身白细胞计数关系。念珠菌26例,曲菌25例,毛霉菌17例,酵母样菌6例。

【Abstract】 The immune organs in 64 cases of child deep mycosis were analysed . Atrophy in the thymuses , spleens, lymph nodes, appendixes and the tonsils was divided into 3 grades according to different degree . Most thymuses showed 3rd grade atrophy , some belonged to 2nd grade , no Ist grade atrophy was found . In the thymuses , Hassall’s corpuscles were concentrated , cystic degeneration , dissociation and calcification were also found. In the severe cases the dissociation of Hassall’s corpuscles was seen in strings . Atrophy of no thymus dependent area was less severe than that in thymus dependent area . The correlation between the reaction in the area invaded by the fungi and the number of peripheral blood leucocytes was discussed . The cases presented in the paper included candidiasis (26 cases), aspergillosis (25 cases), mucormycosis (17cases) and yeast-like fungi infection (6 cases) .

【关键词】 深部真菌病免疫器官萎缩
【Key words】 Deep mycosisImmune organAtrophy
  • 【文献出处】 哈尔滨医科大学学报 ,Journal of Harbin Medical University , 编辑部邮箱 ,1991年02期
  • 【被引频次】1
  • 【下载频次】56
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