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二阶导数光谱法测定复方甲地孕酮微囊注射液中甲地孕酮和戊酸雌二醇含量

Determination of Megestrol Acetate and Estradiol Valerate in Injection of Microencapsulated Compound Megestrol Acetate by Secondary Derivative Spectrophotometry

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【作者】 洪诤陆彬王超凡

【Author】 Hong Zheng;Lu Bin;Wong Chaofan School of Pharmacy

【机构】 华西医大药学院华西医大药学院 湖南省益阳地区药检所进修生

【摘要】 作者来用二阶导数光谱法,同时测定复方甲地孕酮微囊注射液中甲地孕酮和戊酸雌二醇的含量。实验结果表明:两者的平均口收率分别为98.8%和98.0%,变异系数分别为0.71%和1.81%。

【Abstract】 The paper reports the simul-taneous determination of mege?trol aceta-te and estradiol valerate in the injectionof microencapsulated compound meges-trol acetate by secondary derivative spec-trophotometry. The experimental resultsshowed that the average recoveries of thetwo drugs were 98.8% and 98.0%,respec-tively, and that the coefficients of varia-tion were 0.71% and1. 81%, respectively.

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