【摘要】 1987年元月～1990年8月共收治原发性肝癌45例,采取MPU方案治疗23例,有效率为43.48％,白细胞降到4.0×10~9/L以下者3例。MAU方案治疗22例,有效率为40.91％,白细胞降到4.0×10~9L以下者18例。两组治疗后右上腹疼痛均有不同程度的减轻,消化道反应多为轻度。两组从临床表现、分期、分型基本一致,有可比性,统计学处理后见右上腹疼痛缓解率、有效率,胃肠道反应、生存时间均无明显差别(P>0.05)骨髓抑制程度MPU方案明显轻于MAU方案(P<0.01),经分析见两方案均为治疗原发性肝癌较好的方案,临床价值MPU方案优于MAU方案。更多还原

【Abstract】 From January 1987 to August 1990,45 patients with primary liver cancer were treated with MPU and MAU regi-mens: (1)MPU for 23 cases, with a response rate of 43.48% and WBC dropped below 4.0×10~9/Lin 3 cases; (2)MAU for 22 cases with a response rate of 40.91% and WBC dropped below 4.0×10~9/Lin 18 cases. The pain in right upper abdomen in two groups had a greater or lesser alleviate. Gastrointestinal toxicity was not serious. Statistical analysis of the results demonstrated that pain in the right upper abdomen, response rate, survival time and gastrointestin toxicity did not differentiate obviously (p>0.05)and degree of myelosupression of MPU was lower than that of MAU (P<0.01). How-ever,MPU and MAU regimens gave a better therapeutic effect on primary liver cancer,but clinical value of MPU regi-men was better than that of MAU regimen.更多还原