【摘要】 用透射电镜观察人原发性骨肉瘤及其移植瘤的超微结构及碱性磷酸酶的活性变化,实验结果发现第1至第7代移植瘤的超微结构和碱性磷酸酶活性与对照组原发瘤一致;第9代以后的移植瘤的碱性磷酸酶含量明显减少,而细胞超微结构仍具有原发瘤细胞的一些特点,因而证明在本实验条件下,第1至第7代移植瘤可以作为骨肉瘤生物学特性和进一步实验治疗研究的良好材料.更多还原

【Abstract】 Ultrastructure and actived change of akline phosphatase on human steosarcoma and xenotropic are studied.Ultrastructure and activation of akline phosphatase on xenotropic from first to seventh generations are similar to that before transplantation; Akline phosphatases on xenotripic from ninth to seventeenth generations decrease considerally.However, ultrastrueture of tumorous cells continues to have some properties of original osteosarcoma.These observations suggest that the xenotropic from first to seventh generations is a rare experimental model for studing mechanism of disease and cure.更多还原