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地丁紫堇对中枢神经作用的实验研究
Experimental study of effect of Corydalis Bungeana Turcz Total Alkaloid on central nerve
【摘要】 采用光电法、转棒法、化学物质致惊法和直接观察等手段,观察了地丁紫堇总生物碱对中枢神经的作用。结果表明,地丁紫堇总生物碱有镇静、催眠和抗惊厥作用;但与士的宁合用,有易化后者惊厥的作用。小鼠IPLD50为281.00±27.82mg/kg。
【Abstract】 In this paper, the effect of Corydalis Bungeana Turcz total alkaloid on central nerve is studed.The results.show that it has a depressant effect, i.e.sedative, hypnotic and anti-convulsion effects, whereas it increases the convulsant effect of strychnine.The LD50 of it in mice given ip was found to be 281.00±27.82mg / kg.
【关键词】 植物;
药用;
生物碱类/药效学;
中枢神经系统/药物作用;
地丁紫堇;
小鼠;
【Key words】 Corydalis Bungeana Turcz; Hypnotics; Plants, Medicinal; Alcaloids / pharmacodynamics; Central Nervous System / drug effects; Mice;
【Key words】 Corydalis Bungeana Turcz; Hypnotics; Plants, Medicinal; Alcaloids / pharmacodynamics; Central Nervous System / drug effects; Mice;
- 【文献出处】 赣南医学院学报 ,Journal of Gannan Medical College , 编辑部邮箱 ,1991年04期
- 【被引频次】12
- 【下载频次】72