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大孔吸附树脂对尿毒症和烧伤毒血症血浆中分子物质体外吸附的研究
Studies on the Adsorption of Middle Molecular Substances from the Plasma of Uremic Patients and Severe Burnt Patients in Vitro
【摘要】 研究了大孔吸附树脂对尿毒症和烧伤毒血症患者血浆中分子物质的体外吸附,用Sephadex G15柱层析法对血浆中分子物质进行吸附前、后的组分分析,并进行了血浆模拟灌流实验,观察中分子物质的清除率,初步探讨了大孔吸附树脂孔结构对中分子物质的吸附机理。
【Abstract】 It was studied that the middle molecular substances (MMS) were removed with macrop-orous resins from the plasma of uremic patients and severe burnt patients in vitro. The MMS were analyzed with Sephadex G15. The simulated plasma-perfusion was carried out. The efficiency of the clearance of the MMS was investigated. The mechanism of adsorption of the MMS by macroporous resins was discussed. It is helpful for finding and preparing a way to treat the patients with hemoperfu-sion.
【关键词】 大孔吸附树脂;
中分子物质;
尿毒症;
烧伤毒血症;
【Key words】 Macroporous adsorption resin; Middle molecular substance; Uremia; Severe burn tox-aemia;
【Key words】 Macroporous adsorption resin; Middle molecular substance; Uremia; Severe burn tox-aemia;
- 【文献出处】 高等学校化学学报 ,Chemical Research In Chinese Universities , 编辑部邮箱 ,1991年08期
- 【被引频次】5
- 【下载频次】82