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大孔吸附树脂对尿毒症和烧伤毒血症血浆中分子物质体外吸附的研究

Studies on the Adsorption of Middle Molecular Substances from the Plasma of Uremic Patients and Severe Burnt Patients in Vitro

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【作者】 郭贤权于占如何丹史秀萍何炳林吴小兵肖应庆王铁丹

【Author】 Guo Xian-quan, Yu Zhan-ru, He Dan, Shi Xiu-ping, He Bing-lin(Institute of Polymer Chemistry, Nankai University, Tianjin, 300071)Wu Xiao-bing, Xiao Ying-qing, Wang Tie-dan(The First Medical College of the PLA, Guangzhou)

【机构】 南开大学高分子化学研究所中国人民解放军第一军医大学中国人民解放军第一军医大学 天津 300071天津 300071广州广州

【摘要】 研究了大孔吸附树脂对尿毒症和烧伤毒血症患者血浆中分子物质的体外吸附,用Sephadex G15柱层析法对血浆中分子物质进行吸附前、后的组分分析,并进行了血浆模拟灌流实验,观察中分子物质的清除率,初步探讨了大孔吸附树脂孔结构对中分子物质的吸附机理。

【Abstract】 It was studied that the middle molecular substances (MMS) were removed with macrop-orous resins from the plasma of uremic patients and severe burnt patients in vitro. The MMS were analyzed with Sephadex G15. The simulated plasma-perfusion was carried out. The efficiency of the clearance of the MMS was investigated. The mechanism of adsorption of the MMS by macroporous resins was discussed. It is helpful for finding and preparing a way to treat the patients with hemoperfu-sion.

  • 【文献出处】 高等学校化学学报 ,Chemical Research In Chinese Universities , 编辑部邮箱 ,1991年08期
  • 【被引频次】5
  • 【下载频次】82
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