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冷冻干燥辐照灭菌家兔的坐骨神经同种移植的实验研究
EXPERIMENTAL STUDY ON LYOPHLIZED IRRADIATION STERILIZED NERVE ALLOGRAFTS IN RABBITS
【摘要】 利用冷冻干燥辐照灭菌的家兔坐骨神经进行同种移植,结果看到大约76%的动物手术后3个月有较好的形态学(光镜、电镜)和电生理学恢复。神经移植物内神经鞘管的保存、鞘管内Schwann细胞的再建和免疫排斥反应的抑制,是同种神经移植获得成功的关键。
【Abstract】 Lyophylized irraddiation sterilized nerve gafts in rabbits were usedin allogeneic nerve transplatation. The result show that about 76% of experimentalrabbits had fairly well morphologic (microscopic and electron microscopic) and electro-physiological recovery 3 month after operation, Preservation of neurilemmal tubes innerve grafts, repopulation of Schwann cells in this tube and supression of immunerejection are the key pionts in allogenic nerve transplantation.
【关键词】 神经移植;
组织库;
辐照灭菌;
家兔坐骨神经;
【Key words】 Nerve transplantation; Tissue bank; Irradiation sterilization; Sciatic nerve of rabbit;
【Key words】 Nerve transplantation; Tissue bank; Irradiation sterilization; Sciatic nerve of rabbit;
【基金】 国际原子能机构(IAEA)部分资助
- 【文献出处】 辐射研究与辐射工艺学报 ,Journal of Radiation Research and Radiation Processing , 编辑部邮箱 ,1991年04期
- 【被引频次】1
- 【下载频次】25