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垂体后叶素致冠状动脉痉挛症的实验病理学研究

A STUDY OF THE ENZYME ACTIVITY IN ISCHEMIC AREA OF HEART MUSCLES CAUSED BY THE EXPERIMENTAL CORONARY ARTERY SPASM INDUCED BY THE PITUTRIN INJECTION

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【作者】 陈忆九; 张其英; 赵子琴; 李中; 李洪伟;

【Author】 Chen Yijiu Zhang Qiying Zhao Ziqing Li Zhong LiHong Wei Department of Forensic Medicine,Shanghai Medical University 200032

【机构】 上海医科大学法医学教研室; 上海医科大学法医学教研室 200032; 200032;

【摘要】 作者通过大鼠舌下静脉注射垂体后叶素致冠状动脉痉挛,运用组织学、酶组织化学及电镜技术研究冠状动脉痉挛症引起心肌急性缺血的形态学变化特点,同时对大鼠心肌自溶性变化与上述结果进行了分析比较,认为心肌纤维磷钨酸苏木素(PTAH)染色出现不规则横带且伴有心肌间质小血管壁腺苷三磷酸酶(ATPase)活性下降,有助于冠状动脉痉挛症引起心肌缺血的诊断。

【Abstract】 Diagnosis of acute heart ischemia induced by coronary artery spasm(CAS)is not clear yet.We have systematically studied the histopathological,enzyme-histochemical and ultrastructural of the autolytic and the ischemic changes ofthe raf’s heart induced by the injection of the pitutrin into the rat’s sublingualvein.The PTAH stain demonstrated that some irregular transverse bands hadappeared in the muscular fibers.The adenosine triphosphatase activity in smallarteries was decreased.The author suggests that the results are helpful fordignosis of acute heart ischemia caused by CAS.

  • 【文献出处】 中国法医学杂志 ,Chinese Journal of Forensic Medicine , 编辑部邮箱 ,1991年03期
  • 【被引频次】4
  • 【下载频次】78
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