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吸收性止血绫止血作用的实验研究

EXPERIMENTAL STUDIES OF ABSORBABLE STANCHING SATIN (ASS) ON HAEMOSTATIC EFFECT

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【作者】 杨彤苏成业王琍文周琴李春莺张素英

【Author】 Yang Tong Department of Pharmacology, Dalian Medical College

【机构】 大连医学院药理教研室大连医学院药理教研室山西省汾阳高级护校

【摘要】 本实验用家免或犬人工造成肝、脾、股动脉、颈动脉、股二头肌出血创面,贴敷吸收性止血绫(ASS),并以贴敷相似面积与厚度的明胶海绵或纱布作为对照,观察创面出血时间或出血量。证明ASS有显著止血作用,与贴敷纱布相比,可显著缩短出血时间并减少出血量;其止血作用优于明胶海绵。体外凝血试验采用瓷板针挑法或试管法,均证明可缩短凝血时间,与对照的淀粉相比有显著差异,说明ASS对内源性凝血系统有激活作用。

【Abstract】 The experimental studies were examined on oozing blood artificial wounded organs including the liver, spleen, femoral artery, cervical artery and femoral biceps muscles in the rabbits or dogs. Bleeding time and amount of oozing blood were used as indicators as indicators of haemostatic action, We compared the relative potency of absorbable stanching satin (ASS) with absorbable gelatin sponge (AGS) and gauze, the later two materials were used as control. Our results showed that the haemostatic effect of ASS was more powerful than that of AGS or gauze. The blood-coagulation tests were performed in vitro. The results indicated that ASS markedly shortened the coagulation time, this suggested that ASS may have an activated effect on the intrinsic coagulation system.

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