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硒盐维生素C治疗大骨节病效果观察

An Observation on the Therapeutic Effects of Selenium and Vitamin C on Kaschin-Beck Disease

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【作者】 周祥赓王文龙王恩庆余爱玲任永贵徐吉敏吴梅兰周琪姚庆录李兴无蔡官寅汪闻绍

【Author】 Zhou Xiang-geng, et al (Gansu Institute of Endemic Disease Control and Research, Lanzhou)

【机构】 甘肃省地方病防治研究所天水市地方病防治研究所甘肃省地方病防治研究所

【摘要】 本文报告以119例干骺端早期X线改变的大骨节病儿童为对象,观察比较硒和维生素C治疗效果,表明硒的总有效率达80%,与维生素C组和对照组相比,差异显著(P<0.01)。维生素C组,虽有一定疗效,但与对照组比较,差异不显著(P>0.05)。疗效与时间长短、发硒含量关系密切。硒盐是当前补硒防治大骨节病的理想方法。

【Abstract】 An experimental study on the therapeutic effects of selenite and vitamin C therapy on Kaschin-Beck disease in 119 cases of children with early metaphyseal changes by X-ray examination was undertaken. Results showed that the general cure rate of seleniferous salt attained 80%, significantly higher than that of vitamin C administration alone and the control group (P<0.01). Vitamin C therapy seemed to be somehow effective, however, it was not differed from that of the control group statistically (P>0.05). The therapeutic effects were closely associated with the course of disease and the hair selenium contents. It suggested that the supplementation of seleniferous salt be the most effective and feasible measure to control Kaschin-Beck disease at the moment.

【关键词】 大骨节病硒盐维生素C干骺端治疗
【Key words】 Kaschin-Beck diseaseSeleniteVitamin CMetaphyseTherapy
【基金】 联合国儿童基金会资助项目
  • 【文献出处】 地方病通报 ,Endemic Disease Bulletin , 编辑部邮箱 ,1991年02期
  • 【被引频次】11
  • 【下载频次】76
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