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74例霉菌性阴道炎病原菌分析及酮康唑治疗
ISOLATION AND IDENTIFICATION OF PATHOGENIC FUNGI AND ORAL TREATMENT WITH KETOCONAZOLE IN 74 CASES OF MYCOTIC VAGINITIS
【摘要】 本文对74例霉菌性阴道炎患者的阴道分泌物进行了真菌检查,直接镜检阳性率为94.59%,真菌培养阳性率为86.49%,白念球菌占培养阳性的72.72%;伪热带念珠菌占1.52%;类星形念珠菌占3.03%;酵母菌占18.18%,酵母样菌占4.55%。酮康唑治疗其中41例,痊愈率为78.05%,总有效率为100%,不良反应发生率为31.72%。较多的表现为头晕、恶心、皮肤瘙痒,少数表现为头痛、腹痛、腹泻、皮肤起风团,肝功能异常。
【Abstract】 The smears of vagina exudute from 74 patients with mycotic vaginitis were examined by microscope, with a positive detection rate of 94.59%. Then, fungi were confirmed by culture, the fungal growth being positive in 66 cases (89.9%)ineluding 51 cases candida growths(77.27%).The species of candida were isolated ane identified. Among the growing conlonies, candida albicans accounded for 72.72%, candida pseudotropicalis 1.53 % and candida stellatoidea 3.03 %. Moreover, yeast and yeast-like fungs accounted for 18.8%and 4.5 5% of the positive culture, respectively. Forty-one of the 74 patients were treated with ketcconazol, coming up to the cure rate of 78.50%and the total response rate of 100%. Thirteen of the 41 Patients had adverse reactions (31.72%). Most of them showed dizziness, nausea and itching. But headache, diarrhea, abdominal pain, urticariaand liver disturbartce occasionatly occurred.
【Key words】 mycotic vaginitis; yeast; yeast-like; ketoconazole; fungus;
- 【文献出处】 承德医学院学报 ,Journal of Chengde Medical College , 编辑部邮箱 ,1991年01期
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