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74例霉菌性阴道炎病原菌分析及酮康唑治疗

ISOLATION AND IDENTIFICATION OF PATHOGENIC FUNGI AND ORAL TREATMENT WITH KETOCONAZOLE IN 74 CASES OF MYCOTIC VAGINITIS

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【作者】 刘树森阎玉梅贾殿菊金淑娟刘静段昕所蒋青

【Author】 Liu Shusen, et al (Department of Obstetrics anb Gynecology, Affiliated Hospital) Duan Xinsuo, et al (Department of Dermatology, Affiliated Hospital)

【机构】 承德医学院附属医院妇产科承德医学院附属医院妇产科承德医学院附属医院皮肤科

【摘要】 本文对74例霉菌性阴道炎患者的阴道分泌物进行了真菌检查,直接镜检阳性率为94.59%,真菌培养阳性率为86.49%,白念球菌占培养阳性的72.72%;伪热带念珠菌占1.52%;类星形念珠菌占3.03%;酵母菌占18.18%,酵母样菌占4.55%。酮康唑治疗其中41例,痊愈率为78.05%,总有效率为100%,不良反应发生率为31.72%。较多的表现为头晕、恶心、皮肤瘙痒,少数表现为头痛、腹痛、腹泻、皮肤起风团,肝功能异常。

【Abstract】 The smears of vagina exudute from 74 patients with mycotic vaginitis were examined by microscope, with a positive detection rate of 94.59%. Then, fungi were confirmed by culture, the fungal growth being positive in 66 cases (89.9%)ineluding 51 cases candida growths(77.27%).The species of candida were isolated ane identified. Among the growing conlonies, candida albicans accounded for 72.72%, candida pseudotropicalis 1.53 % and candida stellatoidea 3.03 %. Moreover, yeast and yeast-like fungs accounted for 18.8%and 4.5 5% of the positive culture, respectively. Forty-one of the 74 patients were treated with ketcconazol, coming up to the cure rate of 78.50%and the total response rate of 100%. Thirteen of the 41 Patients had adverse reactions (31.72%). Most of them showed dizziness, nausea and itching. But headache, diarrhea, abdominal pain, urticariaand liver disturbartce occasionatly occurred.

  • 【文献出处】 承德医学院学报 ,Journal of Chengde Medical College , 编辑部邮箱 ,1991年01期
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