节点文献
Mg2+和牛磺酸对内皮素促血管平滑肌细胞增殖的影响
THE EFFECT OF Mg2+ AND TAURINE ON ENDOTHELIN-STIMULATED MULTIPLICATION OF VASCULAR SMOOTH MUSCLE CELLS
【摘要】 本工作应用培养的家兔主动脉血管平滑肌细胞,通过细胞计数和3H-胸腺嘧啶核苷参入的方法,观察到内皮素可以刺激血管平滑肌细胞的增殖;同时,内皮素的这种效应可以被Mg2+和牛磺酸拮抗。
【Abstract】 By means of cell counting and 3H-thymidine incorporation we observed that endothlin dose-dependently stimulated the multiplication of rabbit’s aortic smooth muscle cells. And this effect ofendothelin was significantly inhibited by Mg2+ and taurine. The results suggest that taurine and Mg2+may be useful adjunctive drugs for the prevention and freatment of hypertension.
【关键词】 内皮素;
牛磺酸;
镁离子;
血管平滑肌细胞;
【Key words】 Endothelin; Magnesium ion; Taurine; Vascular smooth muscle cells;
【Key words】 Endothelin; Magnesium ion; Taurine; Vascular smooth muscle cells;
- 【文献出处】 北京医科大学学报 , 编辑部邮箱 ,1991年05期
- 【被引频次】14
- 【下载频次】34