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锌对硝基苯所致鼠肝脂质过氧化的保护作用
PROTECTIVE EFFECT OF ZINC FROM LIPID PEROXIDATION INDUCED BY NB IN RAT LIVER
【摘要】 本文报道一次经口给大鼠投予硝基苯后可造成肝细胞的脂质过氧化。给硝基苯后过氧化物含量增加,并且随时间的变化而改变,具有剂量—效应关系。给微量元素锌后对硝基苯造成的脂质过氧化有较好的保护作用,这在防治方面具有一定意义。
【Abstract】 Nitrob-snzene (NB) could induce lipid peroxidation in the liver cells after a single dose of 2000mg/kg of body weight. There was a remarkable positive dose-effect relationship. Trace element zinc showed a protective effect from lipid peroxidation induced by NB in the present experiment. Therefore, zinc is of significance in the prevention and treatment of NB poisoning.
- 【文献出处】 白求恩医科大学学报 , 编辑部邮箱 ,1991年04期
- 【分类号】O614.241;Q554
- 【被引频次】1
- 【下载频次】17