【摘要】 在婴幼儿HBV高感染村,实施一人一针一管一用一消毒的严格措施后,使一岁儿童HBV感染率下降53.0％,HBsAg阳性率下降55.5％,使HBsAg阴性母亲的1～2岁儿童HBV感染率下降64.6％～76.4％,HBsAg阳性率降低78.6％～81.9％。更多还原

【Abstract】 From 1984 to 1990,in a village with 4,000 inhabitants,we investigated the HBV prevalence rate and HBsAg positive rates in children under two years of age in order to determine the prevalence of disinfection of syringes, acupuncture needle, and transfusion sets to HBV infection.The HBV prevalence rates and HBsAg positive rates were 39.4% and 20.9% respectively in one year old babies, and were 36.9% and 11.6% respectively in two years old babies. The village has two small out-patient clinics where five private practioners work. All of them were poorly equipped.The needles of syringe were generally used repeatedly on several patients or sometimes only the needles were changed without change of the syringe. Our study project was to send sterilize syringes, acupuncture needles and transfussion sets by the county anti-epidemic station weekly to the practioners and to enforce strictly the rate of one injection with one syringe and one needle. From 1987-1990 all new-boms and pregnant women were screened by RIA for HBV serologic markers. The results are as follows:One year after application of sterilization measures, the HBsAg of infants bron to HBsAg negative mothers dropped from 15.4% to 3.3%, a decrease in the rate of 78.6%, while in the children 2 years of age bron to HBsAg negative mothers, HBsAg dropped from 11.6% to 2.1%, a decrease of 76.4%. The difference was statistical significant, P<0.001. The results indicate that transmission of HBV in the population through the common usage of needles is one of the important factors in the transmission of HBV.更多还原