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先天性巨细胞病毒、乙型肝炎病毒和弓形体感染的研究

THE STUDY OF CONGENITAL CYTOMEGALOVIRUS, HEPATITIS B VIRUS AND TOXOPLASMA INFECTION

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【作者】 赵澄泉戴淑真邵济钧

【Author】 Zhao Chengquan;Dai Shuzhen;Shao Jijun Department of Microbiology

【机构】 青岛医学院微生物学教研室青岛医学院附属医院妇产科青岛医学院微生物学教研室

【摘要】 对青岛市276例产妇及其新生儿脐血巨细胞病毒(HCMV)抗体,乙型肝炎病毒(HBV)标记物及弓形体抗体进行了检测。产妇HCMV感染率为98.91%,活动性感染率为18.48%;HBV感染率为39.13%;弓形体感染率仅为1.81%。HCMV,HBV和弓形体的先天性感染率分别为3.99%,2.17%和0。从新生儿出生时情况看,HCMV先天性感染所致危害远大于HBV和弓形体。

【Abstract】 Specific antibodies or antigens of human cylomegalovirus (HCMV), hepatitisB virus (HBV) and toxoplasma in 276 cases of maternal sera and in the umbilical cord sera of their newborns in Qingdao city were detected. The result indicatedthat in pregnant women HCMV infection was common (93.91%) and HCMV activeinfection rate was also high (18.48%). The rate of HBV infection was39.13%, while toxoplasma inection rate was only 1.81%. The rates of congenitalHCMV, HBV and toxoplasma were 3.99%, 2.17% and 0 respectively. In viewof newborns, status after birth, the harm caused by HCMV infection was moreserious than that caused by HBV and toxopalsma infection. During the experime-nts we discovered that there was some relationship between the presence ofHBeAg in sesum and HCMV active infection. The exact mechanism needs furtherstudy.

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