【摘要】 通过46例急性脑外伤病人及15只狗的脑外伤模型研究发现,脑外伤后,血及 CSF 中CK、LDH 和 GOT 显著升高。血清酶水平:重度组>中度组>轻度组;脑挫伤组>颅内血肿组>脑震荡组。且血清酶随 GCS 积分下降而升高。结果提示,结合 GCS,血清 CK、和 GOT 可作为判断脑损伤程度的重要生化指标。更多还原

【Abstract】 Serum and CSF creatine kinase(CK),lactic de-hydrogenase(LDH),and glutamic oxaloacetic trans-aminase(GOT)were determined in 46 cases ofacute head injury and 15 experimental dogs.Theresults demonstrated that the CK,LDH,and GOTactivity in CSF and serum increased remarkablyafter head injury.It was higher in case of severehead injury correlated with Glasgow Coma Scale(GCS).It is concluded that,serum GCS,CK.LDH,and GOT may be as the biochemical markers forevaluating the severity of brain injury.更多还原