【摘要】 本文介绍261例垂体腺瘤、52例鞍部其他肿瘤、67例原因不明闭经妇女血清催乳素(PRL)测定结果。嫌色细胞瘤、肢端肥大症和鞍部其他肿瘤引起PRL升高者分别为56.5％、32.9％和34.6％。根据PRL升高程度作者认为超过5000mIU/L(200μg/L)者提示有PRL瘤。PRL瘤约占“嫌色细胞瘤”的1/3左右。PRL中度升高不能肯定是PRL瘤,要结合临床和蝶鞍X线检查考虑。PRL水平和PRL瘤大小呈正相关。原因不明闭经妇女20％伴有高PRL血症,PRL测定有助于早期诊断PRL瘤。更多还原

【Abstract】 Serum prolactin (PRL) levels were studied in 261 patients with pituitary adenomas, 52 patients with other sellar-tumors and 76 patients with amenorrhea. PRL was elevated in 56.5% of patients with chromophobe adenoma,in 32.9% with acromegaly and in 34.6% with other sellar tumors. It is suggested that tne PRL level over 5000 mU/L implys the presence of a prolactinoma. Prolactinoma represents about one third of all chromophobe adenomas. The serum PRL level was found to have a positive correlation with the size of the prolactinoma, thus determination of serum PRL would be helpful in diagnosing prolactinoma in the early stage and in assessment of the effects of the operation and drug treatment.更多还原