【摘要】 在预先引入体内蛋白质标记前身物³⁵S-蛋氨酸后,用宏观和微观放射自显影术,探讨了不同脏器和细胞水平的蛋白质生物合成部位和合成的相对程度。由定位和定量分析研究的结果表明,以肝组织中的蛋白质生物合成能力最强,其次为肾脏、脾脏和大脑,以及骨髓幼稚细胞。而心、肺和骨骼肌等虽具有重要的生理活性,但其蛋白质的生物合成并不旺盛。更多还原

【Abstract】 The purpose of the present study was to observe the incorporation level of 35S-me-thionine by various tissue protein in organism. By the use of the macro and microautora-diographic technique, the incorporation of 35S-methionine by the tissues has been utilized as an index of various tissue protein synthesis. On this basis, the further experiments showed that tracer agent 35S-methionine was dominantly incorporated in the immature cells of bone marrow and the tissue of liver, kidney and spleen. Its incorporation increased gradually with time. From the experimental results it can be concluded that a strong protein biosynthesis metabolism produced in these tissues. While the tissues have important physiological function in organism, such as heart, lung and skeletal muscle, but the protein biosynthesis in those tissues was in a low level.更多还原