节点文献
沙棘果油的急性毒性及其对实验性肝损伤的保护作用
Acute Toxicities of Flesh Oil of Hippophae rhammoides L. and Its Protection Against Experimental Hepatic Injury
【摘要】 沙棘果油对CCl4及扑热息痛诱发肝损伤、肝丙二醛的增高有明显抑制作用,并能降低CCl4中毒小鼠sGPT活力,且能明显对抗扑热息痛中毒小鼠肝谷胱甘肽的耗竭。其LD50>45.0g/kg。
【Abstract】 Protection by flesh oil of Hippophae rhamnoides against hepatotoxicity induced by CCl4 and acetaminophen (AAP) is reported in this paper. It was found that the oil markedly inhibited MDA formation of liver induced by CC14 and AAP, decreased sGPT levels induced by CCl4 and blocked depletion of GSH damaged liver induced by AAP. LD50>45.0g/kg.
- 【文献出处】 中国中药杂志 ,China Journal of Chinese Materia Medica , 编辑部邮箱 ,1990年01期
- 【被引频次】31
- 【下载频次】163