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磁性抗癌药物载体的研制
Study on magnetic microspheres preparation of an antineoplastic drug carrier
【摘要】 磁性微球抗癌药物载体在体外磁场的引导下,能定向移动和固定在肿瘤部位,本文采用单凝聚冻缩法制备出了直径为3~15μm 的磁性微球载体。载体中抗癌药含量为4.5~30%.
【Abstract】 This article presents an antineoplastic drug carrier named magnetic microsph-eres.The carrier of 3~15um in diameter were prepared by using the method of si-ngle coagulation and freeze,which contained antineoplastic agent about 4.5~31% andcould response to extracorporeally placed magnetic field.The experiment also de-monstrated that the magnetic microspheres could be targeted and localized to thetumor.
【关键词】 磁球载体;
靶向给药系统;
单凝聚冻缩法;
【Key words】 magnetic microsphere; antineoplastic drug; carrier; single coagulation-freeze method;
【Key words】 magnetic microsphere; antineoplastic drug; carrier; single coagulation-freeze method;
- 【文献出处】 中国医院药学杂志 ,Chinese Journal of Hospital Pharmacy , 编辑部邮箱 ,1990年01期
- 【被引频次】45
- 【下载频次】159