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改良MTT比色分析法测定乙型肝炎IL-2活性的研究
INTERLEUKIN 2 ACTIVITY IN PATIENTS WITH HEPATITIS B BY MODIFIED MTT COLORIMETRIC ASSAY
【摘要】 用改良MTT比色分析法,测定57例乙型肝炎患者末梢血淋巴细胞在PHA刺激下产生的白细胞介素2(IL-2)活性。各型乙型肝炎IL-2活性明显低于正常人,重症肝炎IL-2活性最低。结果提示:乙型肝炎细胞免疫功能紊乱。
【Abstract】 Using the modified MTT colorimetric assay, we measured the activity ofinterleukin 2(H-2) of periphoral blood lymphecytes activited with phytchac-mogglutin from 57 patients with hepatitis B. The activity of IL-2 in peripheralblood lymphocytes was significantly decreased in all patients. We have comparedthe dada obtained by medified MTT method and ~3H thymidine method andconfirmed that the estimates of IL-2 content were almost same.
- 【文献出处】 中国医科大学学报 ,Journal of China Medical University , 编辑部邮箱 ,1990年S2期
- 【被引频次】2
- 【下载频次】28