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木耳多糖、银耳多糖和银耳孢子多糖对实验性血栓形成的影响
EFFECTS OF POLYSACCHARIDES FROM AURICULARIA AURICULA, TREMELLA FUCIFORMIS AND TREMELLA FUCIFORMIS SPORES ON EXPERIMENTAL THROMBUS FORMATION
【摘要】 兔分别ig木耳多糖、银耳多糖和银耳孢子多糖18.5,27.8和41.7 mg.kg,可明显延长特异性血栓及纤维蛋白血栓的形成时间,缩短血栓长度,减轻血栓湿重和干重,减少血小板数,降低血小板粘附率和血液粘度,并可明显缩短豚鼠优球蛋白溶解时间,降低血浆纤维蛋白元含量,升高纤溶酶活性。结果表明,这三种多糖有明显的抗血栓作用。
【Abstract】 AP, TP and TSP were isolated from Auricularia auricula Underw, Tremella fuciformis Berk and Tremella f uciformis Berks Spores respectively. 18.5 mg/ kg AP, 27.8 mg/ kg TP and 41.7 mg/ kg TSP (ig) remarkedly prolonged characteristic thrombus formation time (CTFT), and thrombus formation time (TFT). The length of thrombus was shortened. Thrombus wet weight, thrombus dry weight, blood platelet count, platelet adherence rate, blood viscosity, cuglobulinlysis timc, and plasma fibrinogcn conccntration wcrc dccrcascd and fibrinolysin vigor activity was spccdcd up by the polysaccharidcs.
【Key words】 Auricularia auricula; Tremella fuciformis; Tremella fuciformis spores; Polysaccharide; Antithrombotic; Reduction blood viscosity;
- 【文献出处】 中国药科大学学报 ,Journal of China Pharmaceutical University , 编辑部邮箱 ,1990年01期
- 【被引频次】67
- 【下载频次】271