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不同脉宽Nd:YAG激光消斑效应的研究

Study of Nd-YAG Laser Radiation on Atherosclerotic plaque

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【作者】 钟华张世华包世宏盖保康郑道声夏罗林程关锠吕剑雄

【Author】 Zhong Hua Zheng Daosheng Zhang Shihua Bao Shihong Gai Baokang (Cardiology Department,Renji Hospital,Shanghai Second Medical University) Xia Luolin Cheng Guanchang (Shanghai Institute of Laser Technology)

【机构】 上海仁济医院心内科激光室上海仁济医院心内科激光室上海市激光技术研究所上海市电子材料公司

【摘要】 本文应用波长1.06μm 的三种不同脉宽的 Nd:YAG 激光,照射总能量300J,分别经空气、血液、生理盐水三种不同介质照射新鲜人尸主动脉粥样斑块片段,结果显示:激光经血液的作用最强烈,空气次之,经盐水几无反应;对斑块的汽化作用以短脉冲组最彻底,对周围组织损伤程度以连续式激光最为严重,短脉冲组最轻。因而认为短脉冲最为适合于选做血管成形术。

【Abstract】 Atherosclerotic plaques of fresh human cadaver in air,blood and saline solutionwere radiated by Nd-YAG laser(1.06μm)with three different pulse duration,at a constant en-ergy level of 300 J respectively.Result revealed that(1)The response of laser is most rapidand severe in the blood and then in the air,there is no response in saline solution within a fewminutes.(2)Short pulse YAG laser vaporizes the atherosclerotic plaque most completely and cau-ses least damage to the adjacent normal vascular tissue,while(3)continuous YAG laser damagethe normal vascular tissue most severely.So,the short pulse YAG laser was considered as theoptional choice for clinical application.

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