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茜草中抗菌活性成分的研究
STUDIES ON ANTIBACTERIAL CONSTITUENTS FROM THE ROOTS OF RUBIA CORDIFOLIA L
【摘要】 从茜草根中分得十二个化合物。通过理化性质及光谱分析,确定了八个已知化合物和一个新化合物(Ⅴ),Ⅴ的结构为1,3,6-三羟基-2-甲基蒽醌-3-O-(O-6′-乙酰基)-β-D-吡喃葡萄糖甙(▽)。
【Abstract】 Twelve compounds were isolated from the roots of Rubia cordifolia L.. Nine of them were established by chemical and spectroscopic methods te be alizarin (Ⅰ), 1-hydroxy-2-methyl-9, 10-anthraquinone (Ⅱ), 1, 3, 6-trihydroxy-2-methyl,-9, 10-anthra-quinone-3-O-(6’-O-acetyl)-α-L-rhamnosyl(1→2)-β-D-glucoside (Ⅲ), 1, 3, 6-trihydrozy-2-methyl-9, 10-anthraquinone-3-O-α-L-rhamnosyl(1→2)-β-D-giucoside(Ⅳ), 1, 3, 6-trihydrozy-2-methyl-9, 10-anthraquinone-3-O-(6’-O-acetyl)-β-D-glucoside(Ⅴ), 2-carbomethoxy -3-prenyl-1, 4-naphthohydroqumone d1-β-D-glucoside(Ⅵ), rubimalim(Ⅶ), β-sitosterel (Ⅷ) and daucosterol (Ⅸ), among them, Ⅴ is a nwe compound and Ⅸ was obtained: from this genus for the first time. Ⅲ, Ⅵ and Ⅶ showed certain antibacterial activities.
【Key words】 Rubia cordifblia L.; 1, 3, 6-Trihydroxy-2-methyl-9, 10-anthraquinone-3-O-(6’-acetyl)-β-D-glucoside; Anthraquinone;
- 【文献出处】 药学学报 ,Acta Pharmaceutica Sinica , 编辑部邮箱 ,1990年11期
- 【被引频次】27
- 【下载频次】328