【摘要】 本文实验结果显示,小鼠在90分钟游泳后,肝组织内过氧化脂质LPO明显增加,超氧化物歧化酶SOD活性明显增高,而且游泳后在肝组织中出现安静时没有的明显的自由基群(g₁₁:2.0424)。更多还原

【Abstract】 This study was designed to determine whether swimming would influence the metabolism of free radical in liver and brain of mice. Male BALB-C mice (34) were randomly assigned to either swimming or control group and were killedeither at rest or after 90 min. of swimming. The lipid peroxidation products (LPO), superoxide dismutase(SOD) and glutathione peroxidase (GSH-Px) activity in the liver and brain were examined. Additionally,the samples of liver were investigated by conventional electron spin resonance techniques. The results showed that swimming increased the LPO production and the activity of SOD, but decreasedthe activity of GSH-Px in the liver of mice. The indices of the mice’s brain were not influenced by swimm-ing, but LPO concentration was significantly higher, and the activity of SOD and GSH-Px was significantlylower than those of the liver. The oxygen-centered free radical with g value 2.0424 was detected in all samp-les of liver from the swimming mice whereas this signal was not seen in ontrol mice. These data suggested that exercise may increase the free radical activity in some but not all tissues.更多还原