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优降糖对实验性糖尿病小鼠胰岛免疫组织化学的影响

Effects of glybenclamide on immunohistochemicalch anges in pancreatic Islets cells of mice with experimental diabetes.

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【作者】 沈桂月文永植李相伍金政

【Author】 Shen Guiyue, Wen Yongzhi, Li Xiangwu, Jin Zheng (Health Center of Yanbian Medical College)

【机构】 卫生所延边医学院组织学与胚胎学教研室

【摘要】 本研究以口服优降糖的实验性糖尿病小鼠作为实验组,以四氧嘧啶糖尿病小鼠作为对照组,分别在病期第7d与第14d取胰腺,用免疫组织化学方法,对胰腺和胰岛B细胞的形态结构进行了观察,结果表明,实验组与对照组之间,未发现明显的形态学差异。

【Abstract】 The mice were divided into two groups, the experiment group, receiving glybenclamide and the control group receiving alloxan by oral administration. The study was carried out by the immunohistochemical method and observed the change of the pancreatic islets and its B cells during the experiment of 7 days and 14 days. The results show that there is no significant defference between the two groups morphologically.

  • 【文献出处】 延边医学院学报 ,Journal of Medical Science Yanbian University , 编辑部邮箱 ,1990年04期
  • 【下载频次】33
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