【摘要】 放射免疫法测定大鼠脑组织中乙酰胆碱含量,大脑皮层和低位脑干分别为27.5±5.24和32.77±3.87,阿托品和东莨菪碱均可使皮层Ach含量显著下降,分别为46％和42％。低位脑干Ach含量亦有下降趋势,但经统计学处理差异无显著性。对降低原因和在生理功能中地位进行了讨论。更多还原

【Abstract】 The Ach content was determined in different parts of rat brain by means of radioimmunoassay.In the cerebral cortex the Ach content was significantly decreased by atropine and scopolamine from 27.53+5.24 to 14.93+1.49 and 15.96+3.59 pmol/mg ( P<0.01 ) .In the lower brain stem tended to decrease too,though the change was statistically insignificant ( from 32.77+3.89 to 29.1+4.34 and 28.35+5.03 pmol/mg respectively, P>0.05). These results may be explained by the possibility that the block takes place at presynapses and results in an increased Ach release.更多还原