【摘要】 胎盘免疫调节肽是一种可透析、可超滤、不耐热的多肽,含有16种氨基酸,分子量为6000以下的小分子物质,疗效与转移因子相似。安全、无毒副作用并对BALB/c小鼠具有促进生长、发育的功能;可使95.2％的PHA皮试阴性者转阳;使因温育37℃而降低的玫瑰花结形成率恢复至活性花结水平,经164例临床应用证明,本品可不同程度地提高患者的细胞免疫功能,是一种比较满意的免疫调节剂。更多还原

【Abstract】 Accroding to the Lawrence’s method, a kind of dialyzable, ultrafil-terable and heat labile polypeptides co-ntaining 16 amino acids were prepared from human placental tissue.Comparative studies revealed that it was not substantially the same as transfer factor(TF), it was considered as a new immune regulator, namely, the placental immunoregulating polypeptides(PIRP). It was safe, had no adverse effects to human body, promoted the growth of BALB/c mice, transformed PHA skin test from negative to positive ia 95.2%cases and recovered the active rosette formation reduced by culture at 37C The improveme-nt of cell-mediated immunological function with PIRP in 164 clinical cases suggested that PIRP is a reasonable immunoregulator.更多还原