【摘要】 研究表明,碳酸铊剂量在0.48mg/kg以上能诱发小鼠骨髓细胞做核数增加;浓度为0.047mg/ml时,诱发体外培养细胞形态转化;剂量为0.83～2.5mg/kg的小鼠致畸试验结果,见胚胎吸收率和胸骨及枕骨缺失(或骨化不全)的胎鼠数明显高于对照组,但未见内脏和外观畸形。更多还原

【Abstract】 The study showed that rats of micronuclei in the bone marrow polychromatic erythrocyte increased obviously in mice received 0.48-4.8mg/kg of thallium carbonate. Morphological trans formation of SHE cells in vitro was observed, when concentration of thallium carbonate in cul ture was 0.047mg/ml. Teratorgenesis test of mouse dimonstrates embryotoxicity, but there is no teratismus occurred when doses were 0.83-2.5mg/kg. Thallium may possibly be potential carci nogenic material.更多还原