【摘要】 用同位素(¹²⁵I-UdR)释放法检测了沙苑子（AC）对正常小鼠和环磷酰胺（Cy）所致免疫抑制小鼠腹腔巨噬细胞（M）介导的肿瘤细胞溶解作用（MTC）和脾细胞NK活性的影响。结果表明AC对正常小鼠的MTC和NK活性无增强作用（P<0.05）。在给小鼠腹腔注射免疫抑制剂Cy（100mg/kg）后,MTC和NK活性均显著下降（P<0.001和P<0.02）。当Cy并用AC（每天8g/kg,连续7天胃饲）后,上述两种细胞毒活性比单用Cy组并无增强,两组间差异无显著性（P>0.05）。更多还原

【Abstract】 The effect of Astragalus Complanatus (AC) on the cyto- toxic activities of peritoneal macrophage (Mφ) and spleen cells in normal and cyclophosphamide-immunosuppressed mice was examined by isotope rel- ease assay (~1251-UdR). The results showed that the AC did not cause any significant change of the MTC and NK cytotoxic activities in normal. After the injection of immunodepressive cyclophosphamide (Cy) alone (ip), the two kinds of cytotoxic activities were decreased (p<0. 001 and p<0. 02 re- spectively). By treatment with both Cy and AC, the cytotoxic activities were not increased as compared with Gy group, and the difference between two groups was not significant (p>0. 05).更多还原