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NORPLANT皮下埋植避孕剂使用的有效性及其副反应的评价

AN EVALUATION OF THE EFFECTIVENESS OF NORPLANT

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【作者】 杜明昆; 郑怀美; CharlesH.C.Chen; L.P.Chow;

【Author】 Du Ming-Kun, et al Family Planning Division, Gyn & Obs. Hospital, Shanghai Medical University, etc.

【机构】 上海医科大学妇产科医院; Emory大学公共卫生学院; Johns Hopkins大学公共卫生学院;

【摘要】 本研究于1984年10月至1987年9月应用Norplant皮下埋植剂1470人(其中Nor-Plant-Ⅰ1169人,Norplant-Ⅱ301人)控制生育。12个月和24个月的避孕效果:累积的妊娠率分别为0.2%和0.3%,持续使用率分别为96.5%和86.2%。主要副反应:月经不规则是终止使用的主要原因;但总失血量不多。Norplant埋植剂使用1年和2年后测定血红蛋白均值略有升高;血压无变化;体重略有增加。埋植剂的放置和取出易于掌握,在1470名使用者中未发生感染或其他并发症,使用安全。由于其妊娠率低和不可能脱落及其高度可逆性,深为受试者所欢迎。

【Abstract】 The study was carried from October 1984 to September 1987, on a total of 1,470 women,including 1,169 Norplant-I and 301 Norplant-II acceptors. The contraceptive results wereobserved. Life table analysis showed that gross cumunative pregnancy rates were 0.2% and0.3%, continuation rates 96.5% and 86.2% at the end of one year and two years res-pectively. The most important side effect during use of Norplant was changes in bleedingpatterns and this was also the most frequent reason for termination. The hemoglobin values of acceptors were found to increase after both 12 monthsand 24 months of use. There was no change in diastolic or systolic blood pressure,and their body weight increased slightly few. The insertion and termination of Norplantcontraceptive implants are not difficult. In 1470 cases of implantation, no infection orcomplication occurred. Also due to the safeness of the method impossibility of unnoticedexpulsion. and low pregnancy rates. The method is well aecepted to Chinese women.

【关键词】 左旋18甲基炔诺酮; 埋植剂; 避孕;
【Key words】 Norplant; Implant; Contraception;
  • 【文献出处】 生殖与避孕 ,Reproduction and Contraception , 编辑部邮箱 ,1990年03期
  • 【被引频次】11
  • 【下载频次】25
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