【摘要】 研究了人工合成胸腺五肽(TP5)的免疫刺激作用。结果表明,TP5对小鼠的脾重和脾组织学都有显著影响。实验组动物脾淋巴细胞的E-玫瑰花结形成率及转化率、PFC皆明显高于对照组动物。讨论了TP5的性质、作用机理和临床应用的前景。更多还原

【Abstract】 This study reported on the systhesis of thymopoietin pentapeptide (TP5) and its biochemical properties. We have investigated the immunostimulatory effect of this artificial systhetic TP5. The results showed that TP5 has markedly promotive influence on weight and histological characteristic of spleen of mice, The transformation, rate of E-rosete formation and plaque forming cell (PFC) of spleen lymphocyte in experimental animal group that were injected TP5 are significantly higher than that of control group. Author discussed mechanism of effect and prospect of clinical trial of TP5 in future.更多还原