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轴突分叉点位置计算法适用性的分析

Analysis of the Feasibility of Calculation Method forthe Estimation of Axonal Branching Point

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【作者】 吕国蔚何国瑞李菁锦

【Author】 Lu Cuowei, He Guorui, Li Qingjin Department of Neurobiology, Capital Institute of Medicine

【机构】 首都医学院神经生物学研究室首都医学院神经生物学研究室

【摘要】 某些中枢神经元通过分叉轴突向两个以上核团投射。轴突分叉点的位置通常由计算轴突主干传导时间予以估测。但是,本工作用该法的4个公式计算细胞内或细胞外记录到的数据未能得到一致和可信的数值。结果提示,计算法的原理是不合理的,并至少对在细胞内或细胞外记录条件下估测轴突分叉点是不适用的。

【Abstract】 Some central neurons project to two or more target nuclei via their branched axons. The location of bifurcation points is usually estimated by calculation of conduction time spent in their parent axons. Howevre, in the present study, no consistant and reliable estimates of the location were shown, when four formulae were used to calculate the data obtained from intra- and extra-cellular recording. The results indicate that the calculation method is inapporpriate in its rationale and not applicable for the evaluation of branching points at least in case of unitary recording fron the ceil body.

【基金】 国家自然科学基金~~
  • 【文献出处】 首都医学院学报 ,Journal of Capital University of Medical Sciences , 编辑部邮箱 ,1990年03期
  • 【下载频次】18
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