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抗人精子抗原的单克隆抗体对人精子穿卵实验的影响
THE EFFECT OF ANTI-HUMAN SPERM MONOCLONAL ANTIBODIES ON THE SPERM PENETRATION ASSAY
【摘要】 利用我所建立的抗人精子抗原的单克隆抗体2A9处理人精子后,进行了3次自身对照性的人精子穿透去透明带金黄地鼠卵实验,共观察了588个卵细胞,受精率从对照组的71%下降到24.5%,P<0.01。证实2A9能使人精子体外穿透功能下降。
【Abstract】 Human sperm hamster ova penetration assay was performed with or without the treatment of sperm by anti-human sperm monoclonal antibodies (MAb) 2A9 which was established by the authors. 588 hamster eggs were observed. Penetration rate was statistically significance between the two rates (P<0.01). Results show that MAb2A9 can effect ability of human sperm to penetrate the hamster ova.
【关键词】 抗人精子抗原;
单克隆抗体;
穿卵实验;
【Key words】 Antisperm antibody; Monoclonal antibody; Egg penetration test.;
【Key words】 Antisperm antibody; Monoclonal antibody; Egg penetration test.;
- 【文献出处】 男性学杂志 , 编辑部邮箱 ,1990年04期
- 【被引频次】1
- 【下载频次】38