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胚胎期缺氧后心肌内去甲肾上腺素的含量变化

THE EFFECT OF PRENATAL HYPOXIA ON THE LEVEL OF NORADRENALINE IN MYOCARDIUM OF NEWBORN RATS

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【作者】 朱珏; 柏蕙英; 陶鄂; 刘通一; 郭强苏; 杨晓明; 顾秀君;

【Author】 Zhu Jue, Bai Huiying et al(Department of Anatomy, Shanghai Second Medical University)

【机构】 上海第二医科大学解剖教研室; 上海第二医科大学解剖教研室;

【摘要】 本文研究了胚胎期缺氧后对新生鼠心肌内去甲肾上腺素(NA)含量的影响,发现缺氧组心肌内NA含量在早期都低于对照组,但心重与体重之比值却高于对照组,尤以5天组最显著,P<0.01。

【Abstract】 Using the hypoxic (15% O2 in N2) pregnant rats (WKY) during the middle gestational period, the effect of the level of Noradrenaline (NA) in myocardium of newborn rats was studied. 27 rats were divided into four groups (1 day, 5 days, 12days and 22 days of age) and compared with the aormal control groups.The result were as follows: the lfvel of NA in myocardium of hypoxic groups (1 day, 5 days and 12 days)were lower that in the control groups, but the ratios of the cardiac weight to body weight in hypoxic groups were higher than that in the control groups.

【关键词】 胚胎; 心肌; 去甲肾上腺素; 缺氧;
【Key words】 fetus; myocardiurn; noradrenaline; hypoxia.;
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