【摘要】 采用红细胞内游离原叶啉(FEP)和FEP/Hb比值对1313名儿童进行铁缺乏症普查,其IDA和IDE发病率分别为33.6％、11.04％。分层抽样108名小儿用多指标综合诊断,其IDA、IDE分别为41.7％、12.96％。两种方法诊断缺铁的患病率差异不显著(P>0.05)。结果表明,FEP不仅适用于大规模人群铁营养状况的筛查,而且在群体防治中可作为监测指标。更多还原

【Abstract】 FEP were measured in 1313 children for iron deficiency investigation, The incid-ence of iron deficiency anamia(IDA) and iron deficiency erythroblast(IDE) are 33.6%, 11.04% respectively. The straitification sampling was made for 108 children in 1313 chi-ldren, Application synthetical diagnosis method, IDA and IDE are 41.7%, 12.96% respe-ctively, there were no significant difficence between incidences of iron deficiency by two diagnostic method(p>0.05), The synthetical diagnostic method sever as golden standard get to sensitivily, specificity, accuracy of FEP and FEP/Hb. The change of Hb, FEP, FEP/Hb, SF was observed, after iron therapy. It is suggested that FEP may be a index of earlier evaluate of treatment of iron deficirncy. The result showed that the FEP may be used for survey of iron deficiency in population, and it is also an im-portamt marker of efficaey of treatment.更多还原