【摘要】 本文比较了不同产地的7种黄连与小檗碱的体外抑菌活性及镇静作用。体外抑菌活性表明,黄连5mg/ml与小檗碱0.5mg/ml比较,除四川巫山及四川石柱黄连外,其它均优于小檗碱。镇静作用表明,各种黄连及小檗碱与生理盐水比较,均有显著差异(p<0.05)而与小檗碱比较无显著差异。更多还原

【Abstract】 We have compared thein vitro bacteriostatic and sedative acti-ons of seven Rhizoma coptidises fromdifferent areas and Berberine. It wasfound that majority of Rhizoma coptidises(5mg/ml) except drugs No. 6 and No. 7are more effective than Berberine(0.5mg/ml) in vitro bacteriostatic test. AIIRhizoma ceptidises and Berberine couldsignificantly decrease the spontaneousactivities of mice (p<0.01, as comparedwith control) , but the difference be-tween Rhizoma coptidises and Berberinewas not significant.更多还原