【摘要】 作者以流产绒毛和外周血淋巴细胞DNA为材料,通过Southern印迹杂交和点杂交,考察了用生物素标记Y特异DNA探针PHY2.1和Cos84进行产前性别诊断的可行性。结果表明:PHY2.1可用于Sou-thern或点杂交,而Cos84只可用于Southern杂交进行产前性别诊断。更多还原

【Abstract】 Using biotinylated human Y-specificDNA probe PHY2.1 and Cos 84, we carriedout Southern and dot hybridization withhuman DNA from artificially aborted cho-rionic villi.and with DNA of peripherallymphocytes from normal male and female.The results show that PHY2.1 may beapplied in prenatal sex identificationboth by Southern and by dot hybridizationbut with Cos 84,only Southern hybridi-zation could be used.更多还原