【摘要】 观察84例胃手术标本肠上皮化生(肠化).发现肠化不仅可起源于胃腺颈部干细胞还能起源于胃腺底部及胃小凹深部的干细胞;肠化与假幽门腺化生有一定联系.肠化也可发生在正常的幽门腺和胃体腺内:并对肠化发展的途径及肠化的性质进行了探讨。更多还原

【Abstract】 Eighty four specimens taken from subtotal gastrectomy of benign or maligantdisorders were gathered to study the intestinal metaplasia (IM) of the gastric mucosaWe found that IM may originate not only from the stem cell at the neck part of thegastric gland. but also from those at the bottom or the gastric gland and at thelower part of the gastric pit.We propose that IM of the gastric mucosa may resultfrom the fault differentiation of the stem cells of the gastric mucosa which normal-ly differentlate into chief cells, parietal cells and mucous cells (including those ofthe pseudopyloric metaplasia gland). Furthermore the developing process andthe nature of the IM were discussed.更多还原