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自校正模型算法控制及其在青霉素发酵中的应用

Self-Tuning Model Algorithm Control and Its Application to Penicillin Fermentation Process

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【作者】 徐萼辉徐国华张嗣良

【Author】 Xu E’hui (Research Institute of Automatic Control) Xu Guohua Zhang Shiliang (Research Institute of Biochemical Engineering)

【机构】 华东化工学院自动化研究所华东化工学院自动化研究所华东化工学院生化工程研究所 浙江大学机械系模具所

【摘要】 针对发酵过程的特点,将参数估计技术引入模型算法控制(MAC),构成自校正模型算法控制,用于时变和非线性的青霉素发酵过程。以在线估计的排气二氧化碳释放率(CER)的脉冲响应模型为基础,进行预测控制,从中求得最佳加糖控制率,使CER跟踪理想变化轨迹,实现对生产的优化控制。仿真结果证明了上述控制算法的可行性和有效性。

【Abstract】 To deal with the fermentation process problem, the technique of parameter estimation is introduced to be combined with the model algorithm control (MAC), resulting in self-tuning MAC. It is then used for the control of penicillin fermentation, which is time-variant and non-linear usually. On the basis of impulse response model of CO2 evolution rate(CER), the process is predicted and the optimal sugar feed rate is determined. Consequently, an optimal control is achieved with a good tracking of ideal CER change, thus leading to an optimal penicillin production. Simulation studies show that the control strategy developed is effective and feasible.

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