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中药治银片对表皮角化及细胞有丝分裂的影响
Effects of tablet Zhi Yin on epidermal keratinization and epithelial mitosis
【摘要】 采用小鼠尾鳞片表皮—小鼠阴道上皮实验模型系统,观察治银片对表皮角化和细胞有丝分裂的影响,探讨治银片治疗银屑病的作用机理。结果证明,治银片具有显著抑制阴道上皮细胞有丝分裂(P<0.01),和促进表皮颗粒层形成(P<0.05)的作用。
【Abstract】 Effects of Chinese materia medica tablet Zhi Yin on epidermal keratinization and epithelial mitosis were examined by means of mouse tail scale epidermis-mouse vaginal epithelium as an experimental model system. It was shown that the drug possessed effects of both inhibiting the mitosis of epithelial cells ( P<0.01 ) and promoting the formation of epidermal granular layer ( P<0.05 ) in c ontrast with the control group given excipients.
【关键词】 角化不全/药物作用;
表皮;
有丝分裂/药物作用;
基底细胞;
牛皮癣;
植物;
药用;
小鼠;
【Key words】 Parakeratosis/drug effects; Epidermis; Mitosis/drug effects; Basal cell; Psoriasis; Plants, medicinai; Mouse;
【Key words】 Parakeratosis/drug effects; Epidermis; Mitosis/drug effects; Basal cell; Psoriasis; Plants, medicinai; Mouse;
- 【文献出处】 赣南医学院学报 ,Journal of Gannan Medical College , 编辑部邮箱 ,1990年02期
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