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大鼠同种颅骨移植物移植后的组织病理学观察
HISTOPATHOLOGICAL STUDY ON ALLOGENEIC SKULL BONE GRAFTS IN RATS
【摘要】 本文介绍用不同剂量辐照灭菌和乙醇灭菌的自溶去抗原同种骨(AAA骨)与未经脱钙和辐照处理的自体及同种骨在移植后组织病理学改变的初步观察结果。以大鼠颅骨缺损为移植模型,于移植2个月后,在光学显微镜下对植入的大鼠颅骨片进行组织病理学观察。结果表明:新鲜自体骨移植效果最好;乙醇灭菌和脱钙4小时、照射15或25kGy剂量的AAA骨次之;而经脱钙24小时、照射25或50kGy的AAA骨最差。
【Abstract】 Using the skull defect of rats as a model for tran-splantation, histopathological observation under light microscope ofallogeneic skull bone grafts treated with different methods were carriedout 2 months after transplantation. The results show that the untreated autogeneic bone grafts are the best in the curative effect of transplantationand followed by the antigen-autolyzed-allogeneic (AAA) bone graftswhich are treated with alcohol for steritization and demireralized for 4h and irradiated at 15 or 25 kGy, but the AAA bone grafts demineralizedfor 24 h and irradiated at 25 or 50 kGy are the bad for transplantation.
【Key words】 Lyophilized Irradiated; Skull Bone; Auto Allaimplant; Histopathology; Rat;
- 【文献出处】 辐射防护 ,Radialization Protection , 编辑部邮箱 ,1990年05期
- 【被引频次】2
- 【下载频次】13