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大骨节病儿童关节软骨蛋白多糖组分构成的定性观察

QUALITATIVE OBSERVATIONS ON THE COMPONENTS OF PROTEOGLYCAN OF ARTICULAR CARTILAGE IN CHILDREN WITH KASHI-BECK DISEASE

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【作者】 张桂琴刘锦先石玉霞谢秀兰刘岩

【Author】 ZHANG GUIQIN et al(Institute of Kashin-Beck Disease, Harbin)

【机构】 中国地方病防治中心黑龙江省防疫站牡丹江地办室 哈尔滨哈尔滨哈尔滨

【摘要】 本文应用盐离子浓度不同的阿尔新蓝染色法,定性观察了正常儿童和大骨节病儿童关节软骨蛋白多糖组分构成不同。看到大骨节病儿童关节软骨硫酸角质素(KS)和硫酸软骨素(CS)都减少,相对(KS)比正常者有增加趋势。并对其可能发生的原因进行了探讨。

【Abstract】 The components of proteoglycan of articular cartilage in children with Kashin-Beck disease were observed by Alcian blue in the different salt solution and compared with that in children with no Kashin-Beck disease. We found that the content of the keraten sulphate and condroitin sulphate of articular cartilage in children with Kashin-Beck disease was reduced but the relative content of keratan sulphate was more than that in normal cartilage. Also we tried to explain the possible reason for the results.

  • 【文献出处】 中国地方病防治杂志 ,Chinese Journal of Control of Endemic Disease , 编辑部邮箱 ,1990年04期
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