【摘要】 通过形态学和立体计量学观察,提出了1种骨肉瘤组织学分型体系。本组将骨肉瘤分为3型:Ⅰ型(骨样组织成熟型),Ⅱ型(骨样组织中等分化型)和Ⅲ型(骨样组织幼稚型)。本组70例骨肉瘤随访50例,最长达20年。Ⅰ型12例,5年存活率为92％,Ⅱ型18例,Ⅲ型20例,皆无5年存活者。统计学处理,Ⅰ型和Ⅱ型,Ⅰ型和Ⅲ型间存活率有显著差异,提示本组分型法对判断预后有意义。而肿瘤部位,大小,细胞组成优势、核分裂相和瘤巨细胞数量与预后无关。更多还原

【Abstract】 A histological classification based on comprehensive morphological and stereometric observation of osteosarcoma was found that osteosarcoma might be divided into three types. Type Ⅰ (mature osteoid type) , Type Ⅱ (intermediate differentiated osteoid type ) and Type Ⅲ (immature osteoid type) . Fifty patients of the seventy were followed up for years, the longest up to twenty years. The five-year survival rate for 12 patients in Type Ⅰ is 92%; for 18 patients in Type Ⅱ and 20 patients in Type Ⅲ, none of them survived more than fiye years after operation. Statistically significant difference is found between individuals in the Type Ⅰ and Type Ⅱ, in Type Ⅰ and Type Ⅲ. The results indicate that the present pathological classification may be correlated with the prognosis. The prognosis of such Type was not correlated with site and size of the tumor, the dominating cellular component, pleomorphism, mito-tic figures and the number of giant cells.更多还原